營運長
張智程 博士
學經歷
Experience
璽邁兒創新恆美診所 營運長
聯醫精準健康管理中心 營運⾧
精準聯醫股份有限公司 董事/研發⾧
聯承管理顧問股份有限公司 執行董事
台北醫學大學 兼任助理教授
桃園市室內設計裝修商業同業公會資訊委員會 副主任委員
台北醫學大學醫學研究所 醫學博士
中央研究院生醫所 博士後研究員
美國UT Southwestern Medical Center 訪問學者
聯醫集團 董事/營運長
聯醫生物科技股份有限公司 董事⾧
佳承精準健康顧問股份有限公司 董事/營運⾧
中壢懷寧醫院醫學研究部 主任
台灣健康管理學會教育委員會 諮議委員
躍穎醫事檢驗所 技術總監
台北市立萬芳醫院 研究醫師
台北醫學大學醫學系 博士後研究員
論文發表 (SCI)
Publications
-
2017, Dec
Hsiu-Chu Chou, Li-Li Wen, Chih-Cheng Chang. Chien-Yu Lin. Lu Jin, Shu-Hui Juan (2017, Dec). From the Cover: 1-Carnitine via PPARy- and Sirtl-Dependent Mechanisms Attenuates Epithelial-Mesenchymal Transition and Renal Fibrosis Caused by Perfluorooctanesulfonate. Toxicological Sciences., 160(2):217-229.
-
2017, May
Chih-Cheng Chang, Yung-Ho Hsu, Hsiu-Chu Chou, Yuan Gii G. Lee, Shu-Hui Juan (2017, May). 3-Methylcholanthrene/Aryl-Hydrocarbon Receptor–Mediated Hypertension through eNOS Inactivation. Journal of Cellular Physiology, 9999: 1-10.
-
2016, May
Li-Li Wen, Chien-Yu Lin, Hsiu-Chu Chou, Chih-Cheng Chang, Hau-Yin Lo, Shu-Hui Juan (2016, May). Perfluorooctanesulfonate Mediates Renal Tubular Cell Apoptosis through PPARgamma Inactivation. PLoS ONE, 11(5), e0155190.
-
2015, Apr
Kur-Ta Cheng, Yu-Shiou Wang, Hsiu-Chu Chou, Chih-Cheng Chang, Ching-Kuo Lee, Shu-Hui Juan (2015, Apr). Kinsenoside-mediated lipolysis through an AMPK-dependent pathway in C3H10T1/2 adipocytes . Phytomedicine, 22, 641-647.
-
2015, Mar
Chih-Cheng Chang, Shu-Hui Juan (2015, Mar). 3-Methylcholanthrene/Aryl-Hydrocarbon Receptor- Mediated Inactivation of eNOS through a RhoA/Akt-dependent Mechanism. Experimental Biology, Boston, MA. USA.
-
2014, Aug
Yuh-Mou Sue, Hsiu-Chu Chou, Chih-Cheng Chang, Nian-Jie Yang, Ying Chou, Shu-Hui Juan (2014, Aug). L-Carnitine Protects against Carboplatin-Mediated Renal Injury: AMPK- and PPARα-Dependent Inactivation of NFAT3. PLoS ONE, 9(8), e104079.
-
2014, Mar
Chih-Cheng Chang, Yuh-Mou Sue, Nian-Jie Yang, Yi-Hsuan Lee, Shu-Hui Juan (2014, Mar). 3-Methylcholanthrene, an AhR Agonist, Caused Cell-Cycle Arrest by Histone Deacetylation through a RhoA-Dependent Recruitment of HDAC1 and pRb2 to E2F1 Complex. PLOS one, 9(3), e92793.
-
2014, Oct
Yung-ho Hsu, Chih-Cheng Chang (co-first author), Nian-Jie Yang, Yi-Hsuan Lee,and Shu-Hui Juan (2014, Oct). RhoA-Mediated Inhibition of Vascular Endothelial Cell Mobility: Positive Feedback Through Reduced Cytosolic p21 and p27. Journal of Cellular Physiology, 229(10), 1455-1465.
-
2013, Jul
Ying Chou, Hui-Chen Lin, Kuan-Chou Chen, Chih-Cheng Chang, Wen-Sen Lee, and Shu-Hui Juan (2013, Jul). Molecular Mechanisms Underlying the Antiproliferative and Antimigratory Effects of Folate on Homocysteine-challenged Rat Aortic Smooth Muscle Cells. British Journal of Pharmacology, 169(7), 1447-1460.
-
2012, Jul
Chih-Cheng Chang, Pei-Shan Lee, Ying Chou, Ling-Ling Hwang, and Shu-Hui Juan (2012, Jul). Mediating Effects of Aryl-Hydrocarbon Receptor and RhoA in Altering Brain Vascular Integrity. The American Journal of Pathology, 181(1), 211-221.
-
2011, Mar
Yuh-Mou Sue, Ching-Feng Cheng, Ying Chou, Chih-Cheng Chang, Pei-Shan Lee, and Shu-Hui Juan (2011, Mar). Ectopic Overexpression of Haem Oxygenase-1 Protects Kidneys from Carboplatin-mediated Apoptosis. British Journal of Pharmacology, 162(8), 1716-30.
-
2010, Nov
Heng Lin, Yuh-Mou Sue, Ying Chou, Ching-Feng Cheng, Chih-Cheng Chang, Hsiao-Fen Li, Chien-Chang Chen and Shu-Hui Juan (2010, Nov). Activation of a Nuclear Factor of Activated T-lymphocyte-3 (NFAT3) by Oxidative Stress in Carboplatin-mediated Renal Apoptosis. British Journal of Pharmacology, 161(7), 1661- 1676.
-
2010, Oct
Heng Lin, Chun-Hsien Yu, Chih-Yu Jen, Ching-Feng Cheng, Ying Chou, Chih-Cheng Chang, Shu-Hui Juan (2010, Oct). Adiponectin-mediated Heme Oxygenase-1 Induction Protects against Iron-induced liver Injury via a PPARα-ependent Mechanism. The American Journal of Pathology, 177(4), 1697- 1709.
-
2010, Mar
Fei-Peng Lee, Chih-Yu Jen, Chih-Cheng Chang, Ying Chou, Heng Lin, Chih-Ming Chou and Shu-Hui Juan (2010, Mar). Mechanisms of Adiponectin-mediated COX-2 Induction and Protection against Iron Injury in Mouse Hepatocytes. Journal of Cellular Physioigy, 224(3), 837-847.
-
2009, Oct
Chih-Cheng Chang, Shih-Ying Tsai, Heng Lin, Hsiao-Fen Li, Yi-Hsuan Lee, Ying Chou, Chih-Yu Jen, Shu-Hui Juan (2009, Oct).
-
2009, Oct
Aryl-hydrocarbon Receptor-dependent Alteration of FAK/RhoA in the Inhibition of HUVEC Motility by 3-methylcholanthrene. Cellular and Molecular Life Sciences, 66(19), 3193-3205.
-
2009, Aug
Yuh-Mou Sue, Chih-Peng Chung, Heng Lin, Ying Chou, Chih-Yu Jen, Hsiao-Fen Li, Chih-Cheng Chang, Shu-Hui Juan (2009, Aug). PPARdelta-mediated p21/p27 Induction via Increased CREB-binding Protein Nuclear Translocation in Beraprost-induced Antiproliferation of Murine Aortic Smooth Muscle Cells. American Journal of Physiology-Cell Physiology, 297, C321-C329.
-
2009, Jul
Yen-Hua Huang, Cheng-Chieh Chin, Hong-Nerng Ho, Chuan-Kai Chou, Chia-Ning Shen, Hung-Chih Kuo, Tsai-Jung Wu, Yu-Chih Wu, Yu-Ching Hung,Chih-Cheng Chang and Thai-Yen Ling (2009, Jul). Pluripotency of Mouse Spermatogonial Stem Cells Maintained by IGF-1-dependent Pathway. The FASEB Journal, 23, 2076-2087.
-
2009, Mar
Yuh-Mou Sue, Ching-Feng Cheng, Chih-Cheng Chang, Ying Chou, Cheng-Hsien Chen and Shu-Hui Juan (2009, Mar). Antioxidation and Anti-inflammation by Haem Oxygenase-1 Contribute to Protection by Tetramethylpyrazine against Gentamicin-induced Apoptosis in Murine Renal Tubular Cells. Nephrology Dialysis of Transplantation, 24(3), 767-777.